Somatic cell cloning in polyester stacks.
نویسندگان
چکیده
منابع مشابه
Human somatic cell nuclear transfer (cloning).
Within 2 years of the announced birth in 1997 of Dolly, the lamb cloned from the mam-mary cells of an adult ewe, research groups announced that they had cloned mice and calves by using differentiated somatic cells (1– 3). In the cloning technique used to produce Dolly, the nucleus of a somatic cell of the ewe was transferred to a sheep oocyte from which the nucleus had been removed, and the cel...
متن کاملRecent advancements in cloning by somatic cell nuclear transfer.
Somatic cell nuclear transfer (SCNT) cloning is the sole reproductive engineering technology that endows the somatic cell genome with totipotency. Since the first report on the birth of a cloned sheep from adult somatic cells in 1997, many technical improvements in SCNT have been made by using different epigenetic approaches, including enhancement of the levels of histone acetylation in the chr...
متن کاملSomatic cell cloning: the ultimate form of nuclear reprogramming?
With the increasing difficulties associated with meeting the required needs for organs used in transplantation, alternative approaches need to be considered. These include the use of stem cells as potential sources of specialized cells, the ability to transdifferentiate cell types in culture, and the development of complete organs that can be used in humans. All of the above goals will require ...
متن کاملCloning animals by somatic cell nuclear transfer – biological factors
Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. However, somatic cloning has been inefficient in all species in which live clones have been produced. High abortion and fetal mortality rates are commonly observed. These developmental defects have been attributed to incomplete reprogramming of the somatic nuclei by the cloning process. Various strateg...
متن کاملSomatic Cell Cloning for Livestock and Endangered Species
It has now been 15 years since the first cloned sheep was born using somatic cell nuclear transfer (SCNT). This technique provides a unique tool for preservation of valuable individuals, livestock propagation, genetically modified animals, production research of biomedicine and conservation of endangered species. In this review, research of the SCNT in livestock and endangered species, includin...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1982
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.79.10.3223